Parliamentary secretary Toru Washizu (Tsuyoshi Kusanagi) has devoted 20 years of his life to Kosuke Inukai, a member of parliament and cabinet minister. Toru works behind the scenes as Inukai's "shadow," deftly handling the petitions of Inukai's supporters and crushing any hint of scandal. Cool and collected, Toru rarely betrays emotion and would humble himself to anyone to get what Inukai needs. But then a shocking event changes everything. Toru's only son, Taiki, is gravely injured in an accident that leaves him close to death. Toru is stricken with worry and fear for his son, but Inukai orders him to conduct a cover-up. Feeling betrayed, Toru, who once would have done anything for Inukai, begins to question everything.

After fending off a series of skilled assassins, gentleman thief Lupin III and his band of allies follow a strange invitation to an uncharted island. When their plane is shot down, the gang is stranded and soon hunted by the island’s inhabitants, past enemies, and a monstrous immortal being known as Muom, who threatens to destroy Lupin's legacy. As a deadly toxic fog settles over them, Lupin must confront his greatest enemy in his most daring escapade yet.